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Tubular Centrifuge for Separating Blood
A tubular centrifuge can be used to separate blood into its components, such as red blood cells, plasma, platelets, and white blood cells. This process is widely used in medical, research, and biopharmaceutical fields. Below are the detailed steps and applications:
Pre-Treatment:
Blood Collection: Collect blood samples in anticoagulant-treated tubes (e.g., EDTA or heparin tubes) to prevent clotting.
Initial Filtration: Filter the blood to remove any large particulate impurities or clots.
Centrifugal Separation:
Feeding: Inject the pre-treated blood into the feeding system of the tubular centrifuge.
Parameter Setting: Adjust the rotational speed (typically 3,000-5,000 rpm for blood separation) to separate blood components based on their densities.
Red Blood Cells (RBCs): Heaviest component, deposited at the bottom.
White Blood Cells (WBCs) and Platelets: Form a thin middle layer (buffy coat).
Plasma: Lightest component, located at the top.
Collection:
Collect plasma through the centrifuge outlet.
Extract the buffy coat for further analysis (if needed).
Collect red blood cells for storage or further processing.
Post-Treatment:
Plasma Processing: Plasma can be further processed to isolate specific proteins (e.g., albumin, immunoglobulins).
Cell Analysis: Red blood cells or white blood cells can be analyzed for medical diagnostics or research purposes.
Equipment Cleaning: Thoroughly clean and sterilize the centrifuge to prevent cross-contamination.
High-Efficiency Separation: Rapid and precise separation of blood components.
High Purity: Enables the isolation of highly pure plasma, red blood cells, or platelets.
Scalability: Suitable for both small-scale laboratory use and large-scale industrial applications.
Flexibility: Adjustable parameters (speed, time) to optimize separation for different blood samples.
Speed and Time: Optimize rotational speed and duration based on the blood sample volume and desired components.
Temperature Control: Use refrigeration (4°C) to maintain blood component integrity during separation.
Aseptic Techniques: Perform all steps in a sterile environment to avoid contamination.
Biosafety: Handle blood samples according to biosafety level (BSL) guidelines, especially when dealing with potentially infectious samples.
Medical Diagnostics: Separation of plasma or serum for clinical tests (e.g., cholesterol, glucose levels).
Blood Banks: Preparation of blood components (e.g., packed red blood cells, platelet-rich plasma) for transfusion.
Biopharmaceuticals: Isolation of plasma proteins (e.g., clotting factors, antibodies) for therapeutic use.
Research: Study of blood cells or plasma components in biomedical research.
Differential Centrifugation: Suitable for basic separation but less precise for isolating specific components.
Density Gradient Centrifugation: Provides higher resolution for separating similar-density components but is more complex and time-consuming.
Filtration: Simple but less effective for separating fine particles or cells.
By using a tubular centrifuge for blood separation, high-purity components can be obtained efficiently, making it a valuable tool in healthcare and research.
|
Model
|
Bowl Speed
(rpm) |
Drum Volume
(L) |
Motor
(KW |
Dimensions, Overall (mm)
|
|
75
|
19000
|
2.2
|
1.5
|
760*450*1120
|
|
105
|
16300
|
6
|
2.2
|
840*500*1600
|
|
125
|
15000
|
8
|
3.0
|
900*550*1600
|
|
150
|
14000
|
10
|
3.0
|
1020*600*1600
|
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